It is possible to get up to 6 months of use out of a single tube of prescription Premarin Vaginal Cream depending on the dose given. Efficacious doses of estrogen should be administered for the shortest possible time period compatible with the treatment goals and risks of the individual woman being treated.
Can you use Premarin long term?
A modest increase in the risk of ovarian cancer has been seen in women who have used estrogen-only or combination estrogen-progestin hormone replacement therapy for a long period of time. According to the Million Women Study, 5 years of HRT resulted in one more case for every 2500 users of the drug.
What happens when you stop using Premarin cream?
The recurrence of menopausal symptoms, particularly hot flashes, is one of the potential side effects of discontinuing hormone replacement treatment. If there are any symptoms, they may be more controllable than they were before HRT was introduced. Women who quit taking hormone replacement therapy may endure bothersome symptoms that are difficult to alleviate.
How long should you use estrogen cream?
Typically, your doctor will recommend that you use this medication for only three weeks out of every month (three weeks on and one week off). Your doctor may decide to raise your dose if it is necessary.
What are the long term effects of Premarin?
In the event of any serious side effects, such as mental or mood changes (such as depression or memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach or intestinal pain, call your doctor right away at 1-800-222-1222.
At what age should you stop taking Premarin?
If you are in good health, the majority of specialists believe that using HRT at the lowest effective dose for the shortest period of time is safe. If you are 59 years old or older, or if you have been taking hormones for more than 5 years, you should consult your doctor about stopping.
Does Premarin cream go bad?
Do not use this medication after the expiration date (EXP) indicated on the package, or if the packaging is broken or exhibits evidence of tampering with the product. Please return it to your pharmacist for disposal if it has expired or has been damaged. If you are unsure whether or not you should begin taking this medication, speak with your doctor about it.
What is the best alternative to Premarin?
What is the most effective substitute for Premarin? Estrace is a medication that is comparable to Premarin. Other estrogen-containing drugs include the Vivelle Dot Patch, the Climara Patch, and vaginal estrogen in the form of Vagifem vaginal tablets (vaginal tablets used with a vaginal applicator) or the Estring Vaginal Ring, among other options.
How long does Premarin stay in your system?
These metabolites have an average half-life (the amount of time it takes for half of the active drug to be removed from the body) ranging from 11.4 to 26.5 hours on average. It takes between two and four weeks for conjugated estrogens to make a substantial difference in menopausal symptoms.
Is there a natural alternative to estrogen cream?
One recent experiment found that using a vaginal suppository that included the hormone known as DHEA as an alternative to estrogen for addressing vaginal difficulties associated with menopause was a viable option.
Can I use Premarin cream every day?
PREMARIN Vaginal Cream is applied intravaginally and delivered in a cyclic fashion ( daily for 21 days and then off for 7 days ). Generally speaking, ladies should begin with a 0.5 g dose strength. Individual response may necessitate dosage modifications (0.5 to 2 g) [see Dosage Forms and Strengths for further information].
What happens if you use too much estrogen cream?
Females who get an excessive amount of estrogen may have nausea and vomiting, as well as withdrawal bleeding. In most cases, the recommended dose range for Estrace Vaginal Cream is 2 to 4 g (as indicated on the applicator) twice a day for one or two weeks, followed by a progressive reduction to half the initial dosage for a comparable amount of time.
What does Premarin do to your body?
Premarin is a medication that is used to treat menopause symptoms such as hot flashes and vaginal changes, as well as to prevent osteoporosis (bone loss) in postmenopausal females. Also known as estrogen replacement therapy, Premarin is used to treat women who have ovarian failure or other diseases that cause their bodies to produce insufficient amounts of natural estrogen.
Where do you rub estrogen cream?
If you are using estradiol gel, you should apply it in a thin layer to one arm, starting at the wrist and working your way up to your shoulder. Use estradiol emulsion on both your thighs and calves if you are going to be utilizing this product (lower legs). Applying estradiol gel or emulsion on your breasts is not recommended.
Does Premarin cause dementia?
However, following unfavorable findings from many big multicenter trials a decade ago, its use has declined dramatically. Those aged 65 to 79 who were randomly allocated to PremPro (Premarin plus progestin) had double the risk of dementia as women on a placebo, according to a 2003 study published in the Journal of the American Medical Association.
Does Premarin make you gain weight?
There is no evidence that hormone replacement therapy causes weight gain or weight reduction. In most cases, women reach menopause between the ages of 45 and 55 years old. After a woman’s final menstrual cycle, she will experience this condition around one year later. In women going through the menopausal transition, the production of hormones generated by the ovaries is affected.